Volume 5, Number 3 (17 2006)                   ijdld 2006, 5(3): 271-280 | Back to browse issues page


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Mahmoudi M J, Saghafi H, Fakhrzadeh H, Heshmat R, Shafaei A, Larijani B. PREVALENCE OF LIPID DISORDERS AMONG RELATIVES OF PATIENTS WITH PREMATURE CORONARY ARTERY DISEASE. ijdld. 2006; 5 (3) :271-280
URL: http://ijdld.tums.ac.ir/article-1-368-en.html

Abstract:   (4794 Views)
Background: Dyslipidemia accounts as a major risk factor for cardiovascular diseases. The aim of this survey was to determine the prevalence of dyslipidemia among relatives of patients with premature coronary artery disease (PCAD).
Methods: As a cross-sectional study 232 first degree relatives of patients with PCAD were recruited. A questionnaire was filled out by all of the participants all of them undergone physical examination and blood sampling. Lipid profile was categorized according to the NCEP: ATPIII criteria.
Results: Total Cholesterol>200 in 29.7%, LDL>160 in 10.3%, HDL<40 in 12.9%, TG>200 in 32.8%, ApoB100>130 in 14.2%, Apo A1<90 in 1.7% and LP(a)>30 in 47% of participants were seen. Serum levels of TG were significantly higher in men than women levels of HDL and ApoA1 were lower in men than women. The Prevalence of dyslipidemia among relatives was 59.6%.
Conclusion: In view of high prevalence of Dyslipidemia among relatives of PACD patients, active interventions in order to primary prevention of cardiovascular diseases via exact screening is recommended.
Full-Text [PDF 303 kb]   (1142 Downloads)    
Type of Study: Research | Subject: General
Received: 2005/10/12 | Accepted: 2006/03/16 | Published: 2013/10/3

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