Volume 5, Issue 4 (17 2006)
ijdld 2006, 5(4): 319-324 |
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Javad Zavar Reza, Mahmoud Dousti, Sadigheh Soleimani, Farzad Asadi Jamnani, Bardia Farzamfar, Shahrnaz Aria Barzin et al . EFFECTS OF PERSIAN WALNUT (LAVASANATREGION) OIL EXTRACT ON LIPID PROFILE IN ANIMAL MODEL (HYPERCHOLESTEROLEMIC MALE RATS). ijdld 2006; 5 (4) :319-324
URL: http://ijdld.tums.ac.ir/article-1-348-en.html
URL: http://ijdld.tums.ac.ir/article-1-348-en.html
Javad Zavar Reza 
, Mahmoud Dousti * 1, Sadigheh Soleimani , Farzad Asadi Jamnani , Bardia Farzamfar , Shahrnaz Aria Barzin , Ali Jalilian
, Mahmoud Dousti * 1, Sadigheh Soleimani , Farzad Asadi Jamnani , Bardia Farzamfar , Shahrnaz Aria Barzin , Ali Jalilian
Abstract: (9445 Views)
Background: Experimental studies have shown that walnut (Juglans regia) intake decreases the risk of coronary heart disease (CHD). Walnut decreases the levels of atherogenic lipids such as TG, LDL-C and VLDL-C. Mainly the effect is induced via 3- Poly Unsaturated Fatty Acids (3-PUFA). Walnuts are a rich source of these fatty acids, especially -Linolenic acid (C18:3 9, 12, 15).
Methods: We assigned 20 hypercholesterolemic male Rats (200-250g) to four groups, and fed with four diet concentration of oil extract Persian walnuts(J. regia)(Lavasanate) (w/w ) as complementary diet: control group (0% oil extract) and cases 5%(1g oil extract/1g weight/1 day) ,7.5%(1.5g oil extract/1g weight/1 day),10%(1g oil extract/1g weight/1 day) for eight weeks.
Results: Results revealed there is a positive effect on the decreasing of TG(14%) ,TC(7.8%) , LDL-C(11%),VLDL-C(12%) serum concentrations, with increasing consumption of oil extract Persian walnuts (5% ,7.5% and 10%).
Conclusion: In view of the positive effect of oil extract Persian walnuts (J. regia) consumption on decrease serum concentration of TG, TC, LDL-C and VLDL-C known as atherogenic lipids and lipoproteins, it may be suggested as a CHD protective dietary supplement.
Methods: We assigned 20 hypercholesterolemic male Rats (200-250g) to four groups, and fed with four diet concentration of oil extract Persian walnuts(J. regia)(Lavasanate) (w/w ) as complementary diet: control group (0% oil extract) and cases 5%(1g oil extract/1g weight/1 day) ,7.5%(1.5g oil extract/1g weight/1 day),10%(1g oil extract/1g weight/1 day) for eight weeks.
Results: Results revealed there is a positive effect on the decreasing of TG(14%) ,TC(7.8%) , LDL-C(11%),VLDL-C(12%) serum concentrations, with increasing consumption of oil extract Persian walnuts (5% ,7.5% and 10%).
Conclusion: In view of the positive effect of oil extract Persian walnuts (J. regia) consumption on decrease serum concentration of TG, TC, LDL-C and VLDL-C known as atherogenic lipids and lipoproteins, it may be suggested as a CHD protective dietary supplement.
Keywords: Oil extract of Persian walnut, Lipid profile, Coronary heart disease, Hyper-cholestrolemic Male Rat
Type of Study: Research |
Subject:
General
Received: 2006/02/18 | Accepted: 2006/06/23 | Published: 2013/10/3
Received: 2006/02/18 | Accepted: 2006/06/23 | Published: 2013/10/3
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