Volume 13, Issue 5 (7-2014)
ijdld 2014, 13(5): 393-399 |
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Foruotan B, Molzemi S, Harati por H, Molzemi S, Bolbol haghighi N, Alam al-Hoda F S, et al . EVALUATION OF PALMATINE EFFECTS ON CUTANEOUS WOUND HEALING IN NORMAL AND DIABETIC RATS. ijdld 2014; 13 (5) :393-399
URL: http://ijdld.tums.ac.ir/article-1-5251-en.html
URL: http://ijdld.tums.ac.ir/article-1-5251-en.html
Behzad Foruotan1 
, Sahar Molzemi * 2, Hoosin Harati por3 , Shahram Molzemi4 , Nahide Bolbol haghighi5 , Fatemeh Sadat Alam al-Hoda6 , Amir Hossein Ashenaii7 , Seyed Reza Mousavi7 , Mohammad Reza Jafari7 , Mohsen Choopani Moghaddam7
, Sahar Molzemi * 2, Hoosin Harati por3 , Shahram Molzemi4 , Nahide Bolbol haghighi5 , Fatemeh Sadat Alam al-Hoda6 , Amir Hossein Ashenaii7 , Seyed Reza Mousavi7 , Mohammad Reza Jafari7 , Mohsen Choopani Moghaddam7
1- 1. Shahroud University of Medical Sciences, Shahroud, Iran
2- 2. School of Medical Sciences, Islamic Azad University, Shahrood Branch, Shahrood, Iran ,saharmolzemi@yahoo.com
3- 3. School of Medicine, Shahrood University of Medical Sciences, Shahrood, Iran
4- 4. Shahrood University of Technology, School of Electronic Training
5- 5. Shahroud University o f Medical Sciences, Faculty of Medicine, Department of Obstetrics
6- 6. Department of Physiology, Islamic Azad University, Damghan, Iran
7- 7. School of Medical Sciences, Islamic Azad University, Shahrood Branch, Shahrood, Iran
2- 2. School of Medical Sciences, Islamic Azad University, Shahrood Branch, Shahrood, Iran ,
3- 3. School of Medicine, Shahrood University of Medical Sciences, Shahrood, Iran
4- 4. Shahrood University of Technology, School of Electronic Training
5- 5. Shahroud University o f Medical Sciences, Faculty of Medicine, Department of Obstetrics
6- 6. Department of Physiology, Islamic Azad University, Damghan, Iran
7- 7. School of Medical Sciences, Islamic Azad University, Shahrood Branch, Shahrood, Iran
Abstract: (8271 Views)
Background: Finding effective drugs is considered for healing diabetic wounds by researchers. The purpose of this study is to evaluate the wound healing effects of palmatine in the healing of skin wounds in normal and diabetic rats.
Methods: In this study 16 male Wistar rats were dهvided into four groups (Negative control, Positive control, The first experimental,The second experimental) . A 4 cm2 wound was created in the left side of the spinal cord in each of these groups and the process of wound healing was macroscopically evaluated.
Results: The wounds of the diabetic groups (the diabetes was coused by streptozocin) showed longer healing process in comparison with the normal groups and the wound healing in the experimental groups which were treated by palmitine was faster in comparison with the control group.
Conclusions: the results showed that palmatine speeds the wound healing up in normal and diabetic samples.
Type of Study: Research |
Subject:
General
Received: 2014/11/1 | Accepted: 2014/11/1 | Published: 2014/11/1
Received: 2014/11/1 | Accepted: 2014/11/1 | Published: 2014/11/1
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