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1- Islamic Azad University Branch of Ilam
2- Islamic Azad University Branch of Ilam , htaheriedu@gmail.com
Abstract:   (270 Views)
Background: Type 2 diabetes mellitus, like other inflammatory diseases, causes a change in the levels of pro-inflammatory (such as gremlin-1) and anti-inflammatory (such as pentraxin-3) markers. The aim of the present study was to compare the effects of 10 weeks of aerobic and resistance training on serum levels of pentraxin-3, gremlin-1 and insulin resistance in men with type 2 diabetes.  
Methods: In this semi-experimental study, 29 men with type 2 diabetes in the age range of 25-45 years were selected and randomly divided into three groups: aerobic training, resistance training and control. Aerobic training program with an intensity of 55-75% of the maximum heart rate and resistance training with an intensity of 55-75% of one repetition maximum was implemented during 10 weeks and 3 sessions per week. Before and after the intervention period, serum levels of pentraxin-3, gremlin-1 were measured and also insulin resistance index was calculated.
Results: In both aerobic (P=0.039) and resistance (P=0.019) training groups, pentraxin-3 serum level increased significantly compared to the control group; but there was no difference between the two groups (P=0.703). Also, serum levels of gremlin-1 and insulin resistance of the aerobic (P=0.022 and P=0.040, respectively) and resistance (P=0.037 and P=0.031, respectively) training groups showed a significant decrease compared to the control group; Although there was no difference between the training groups (P=0.815 and P=0.659, respectively).
Conclusion: This findings demonstrate that both types of aerobic and resistance training are equally effective in improving inflammatory markers and insulin resistance in type 2 diabetes patients.
Article number: 2
     
Type of Study: Research | Subject: Special
Received: 2023/08/25 | Accepted: 2023/11/26

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