Iranian Journal of Diabetes and Lipid Disorders
مجله دیابت و متابولیسم ایران
ijdld
Medical Sciences
http://ijdld.tums.ac.ir
1
admin
2345-4008
2345-4016
000
000
000
000
000
fa
jalali
1402
6
1
gregorian
2023
9
1
23
3
online
1
fulltext
fa
تأثیر هشت هفته تمرینهای مقاومتی دایرهای و تمرینهای تداومی با شدت متوسط بر شاخصهای متابولیکی و سطح سرمی سیرتوئین 1 در زنان مبتلابه سندرم متابولیک
The Effect of Eight Weeks’ Circuit Resistance Training and Moderate Intensity Continuous Training on Metabolic Indices and Sirtuin1 Serum Level in Women with Metabolic Syndrome
عمومى
General
پژوهشي
Research
<span style="font-size:11pt"><span style="line-height:92%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:"><span style="color:black">مقدمه</span></span></span></span></b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:"><span style="color:black">: </span></span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:"><span style="color:black">زنان در طی دوران یائسگی، بیش از پیش در معرض عوامل خطر بسیاری از بیماریها از جمله سندرم متابولیک قرار دارند و سیرتوئین 1 ممکن است در این اختلال درگیر باشد. هدف این مطالعه بررسی تأثیر تمرینهای مقاومتی دایرهای و تمرینهای تداومی با شدت متوسط بر شاخصهای متابولیکی و سطح سرمی سیرتوئین 1 در زنان مبتلابه سندرم متابولیک بود.</span></span></span></span><b><span dir="LTR" lang="X-NONE" style="font-size:12.0pt"><span style="line-height:92%"><span new="" roman="" style="font-family:" times=""><span style="color:black"></span></span></span></span></b></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="line-height:92%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span style="color:black"><b><span lang="AR-SA" style="line-height:92%"><span b="" lotus="" style="font-family:">روشها: </span></span></b><span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">این مطالعه بهصورت کارآزمایی بالینی در زنان مبتلابه سندرم متابولیک در دو گروه مداخله (15 نفر گروه </span></span><span lang="AR-SA" style="line-height:92%"><span b="" lotus="" style="font-family:">تمرینها</span></span><span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">ی مقاومتی و 15 نفر گروه </span></span><span lang="AR-SA" style="line-height:92%"><span b="" lotus="" style="font-family:">تمرینها</span></span><span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">ی تداومی) و یک گروه کنترل (15 نفر) انجام گردید. گروه مداخله تحت برنامۀ تمرینی به مدت هشت هفته و سه جلسه در هفته، قرار گرفتند و گروه کنترل برنامۀ معمول روزانه خود را داشتند. پس از آخرین جلسۀ تمرین میزان سطوح سرمی سیرتوئین1 و فاکتورهای لپیدی اندازهگیری شد. برای تجزیهوتحلیل دادهها از آزمون تی زوجی و از کوواریانس در سطح معنیداری (05/0</span></span><span lang="FA" style="line-height:92%">≥</span><span dir="LTR" lang="X-NONE" style="font-size:10.0pt"><span style="line-height:92%">P</span></span><span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">) استفاده شد.</span></span></span></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="line-height:92%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span style="color:black"><b><span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">یافتهها: </span></span></b><span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">نتایج آزمون تی نشان داد که تفاوت معنی</span></span><span lang="FA" style="line-height:92%"><span cambria="" style="font-family:"></span></span><span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">داری در تغییرات درون</span></span><span lang="FA" style="line-height:92%"><span cambria="" style="font-family:"></span></span><span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">گروهی متغیرهای مورد بررسی (سیرتوئین1 (</span></span><span dir="LTR" lang="X-NONE" style="font-size:10.0pt"><span style="line-height:92%">SIRT1</span></span><span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">)، لیپوپروتئین با چگالی بالا (</span></span><span dir="LTR" lang="X-NONE" style="font-size:10.0pt"><span style="line-height:92%">HDL</span></span><span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">)، لیپوپروتئین با چگالی پایین (</span></span><span dir="LTR" lang="X-NONE" style="font-size:10.0pt"><span style="line-height:92%">LDL</span></span><span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">)، تریگلیسرید (</span></span><span dir="LTR" lang="X-NONE" style="font-size:10.0pt"><span style="line-height:92%">TG</span></span><span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">)، قند خون ناشتا (</span></span><span dir="LTR" lang="X-NONE" style="font-size:10.0pt"><span style="line-height:92%">FBS</span></span><span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">)، کلسترول تام (</span></span><span dir="LTR" lang="X-NONE" style="font-size:10.0pt"><span style="line-height:92%">Total Cholesterol</span></span><span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">) در هر دو گروه تمرینی وجود داشت (05/0</span></span><span lang="FA" style="line-height:92%">≥</span><span dir="LTR" lang="X-NONE" style="font-size:10.0pt"><span style="line-height:92%">P</span></span><span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">)، اما در گروه کنترل تفاوت معنیداری مشاهده نشد (05/0<</span></span><span dir="LTR" lang="X-NONE" style="font-size:10.0pt"><span style="line-height:92%">P</span></span><span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">). نتایج آزمون کوواریانس نشان داد در پسآزمون بین سه گروه در شاخصهای (</span></span><span dir="LTR" lang="X-NONE" style="font-size:10.0pt"><span style="line-height:92%">SIRT1</span></span> <span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">،</span></span><span dir="LTR" lang="X-NONE" style="font-size:10.0pt"><span style="line-height:92%">HDL</span></span><span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">، </span></span><span dir="LTR" lang="X-NONE" style="font-size:10.0pt"><span style="line-height:92%">LDL</span></span> <span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">،</span></span><span dir="LTR" lang="X-NONE" style="font-size:10.0pt"><span style="line-height:92%">TG</span></span> <span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">،</span></span><span dir="LTR" lang="X-NONE" style="font-size:10.0pt"><span style="line-height:92%">FBS</span></span> <span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">،</span></span><span dir="LTR" lang="X-NONE" style="font-size:10.0pt"><span style="line-height:92%">Total</span></span> <span dir="LTR" lang="X-NONE" style="font-size:10.0pt"><span style="line-height:92%">Cholesterol</span></span><span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">) تفاوت معنیداری وجود دارد (05/0></span></span><span dir="LTR" lang="X-NONE" style="font-size:10.0pt"><span style="line-height:92%">P</span></span><span lang="FA" style="line-height:92%"><span b="" lotus="" style="font-family:">).</span></span><span lang="AR-SA" style="line-height:92%"><span style="font-family:"B Lotus""></span></span></span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:92%"><span style="tab-stops:right 0cm"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">نتیجهگیری: </span></span></span></b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">هشت هفته برنامۀ </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:"><span style="color:black">تمرینهای</span></span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:"> مقاومتی دایرهای و </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:"><span style="color:black">تمرینهای</span></span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:"> تداومی با شدت متوسط، تأثیر مثبتی بر شاخصهای متابولیکی و سطح سرمی سیرتوئین 1 افراد مبتلابه سندرم متابولیک دارد.</span></span></span><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus""></span></span></span></b></span></span></span></span></span></span>
<span style="font-size:11pt"><span style="line-height:normal"><span style="text-autospace:none"><span sans-serif="" style="font-family:Calibri,"><b><span new="" roman="" style="font-family:" times="">Background:</span></b><b> </b><span new="" roman="" style="font-family:" times="">During menopause, women are more exposed to the risk factors of many diseases, including metabolic syndrome, and sirtuin-1 may be involved in this disorder. The aim of this study was to investigate the effect of circular resistance training and moderate intensity continuous training on metabolic indices and Sirtuin1 serum level in women with metabolic syndrome.</span><b><span style="font-family:"TimesNewRomanPSMT","sans-serif""></span></b></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:normal"><span style="text-autospace:none"><span sans-serif="" style="font-family:Calibri,"><b><span new="" roman="" style="font-family:" times="">Methods: </span></b><span new="" roman="" style="font-family:" times="">This study was conducted as a clinical trial in women with metabolic syndrome in two intervention groups (15 people in resistance training group and 15 people in continuous training group) and a control group (15 people). The intervention group underwent an exercise program for eight weeks and three sessions per week, and the control group had their own routine program. After the last training session, serum levels of Sirtein1 and lipid factors were measured. To analyze the data, t-test and covariance were used at a significant level (P≤0.05).</span><span new="" roman="" style="font-family:" times=""><span style="color:black"></span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:normal"><span sans-serif="" style="font-family:Calibri,"><b><span new="" roman="" style="font-family:" times=""><span style="color:black">Results</span></span></b><b><i><span new="" roman="" style="font-family:" times=""><span style="color:black">:</span></span></i></b><span new="" roman="" style="font-family:" times=""><span style="color:black"> The results of the t-test showed that there was a significant difference in the intra-group changes of the studied variables (SIRT1, HDL, LDL, TG, FBS, Total Cholesterol) in both exercise groups (P≥0.05), but in No significant difference was observed in the control group (P<0.05). The results of the covariance test showed that there is a significant difference between the three groups in the indices (SIRT1, HDL, LDL, TG, FBS, Total Cholesterol) after the test (P<0.05).</span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:normal"><span style="text-autospace:none"><span sans-serif="" style="font-family:Calibri,"><b><span lang="EN" new="" roman="" style="font-family:" times="">Conclusion<i>:</i></span></b><span lang="EN" new="" roman="" style="font-family:" times=""> Eight weeks of circular resistance training program and continuous training with moderate intensity has a positive effect on metabolic indices and serum level of Sirtuin1 in people with metabolic syndrome.</span><span style="font-family:"Times New Roman","serif""></span></span></span></span></span>
شاخصهای متابولیکی, زنان یائسه, تمرینهای ورزشی
Metabolic Indicators, Menopausal Women, Physical Activity
168
178
http://ijdld.tums.ac.ir/browse.php?a_code=A-10-1959-1&slc_lang=fa&sid=1
Saeid
Shamlou Kazemi
سعید
شاملو کاظمی