Iranian Journal of Diabetes and Lipid Disorders
مجله دیابت و متابولیسم ایران
ijdld
Medical Sciences
http://ijdld.tums.ac.ir
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admin
2345-4008
2345-4016
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jalali
1403
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gregorian
2024
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تأثیر بازتوانی همراه با مصرف ویتامین D بر خستگی، کیفیت خواب و میزان افسردگی افراد مبتلا به سرطان استئوسارکوم پس از پیوند سلولهای بنیادی مغز استخوان
The Effect of Rehabilitation With Vitamin D Consumption on Fatigue, Sleep Quality and Depression of People with Osteosarcoma Cancer After Bone Marrow Stem Cell Transplantation
تخصصي
Special
پژوهشي
Research
<span style="font-size:11pt"><span style="line-height:92%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">مقدمه</span></span></span></b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">: هدف پژوهش حاضر، بررسی تأثیر بازتوانی همراه با مصرف ویتامین </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%"><span new="" roman="" style="font-family:" times="">D</span></span></span><span style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:"> بر خستگی، کیفیت خواب و میزان افسردگی افراد مبتلا به سرطان استئوسارکوم پس از پیوند سلولهای بنیادی مغز استخوان بود.</span></span></span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:92%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">روشها:</span></span></span></b> <span lang="FA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">در این مطالعه، 27 زن </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">مبتلا به سرطان استئوسارکوم</span></span></span> <span lang="FA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">با نمایۀ تودۀ بدنی بالای 30کیلوگرم برمترمربع، سن 03/4</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:92%"><span cambria="" style="font-family:">±</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">90/24 سال، قد 62/3</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:92%"><span cambria="" style="font-family:">±</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">85/163 سانتیمتر و وزن 5/4</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:92%"><span cambria="" style="font-family:">±</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">17/82 کیلوگرم</span></span></span><b> </b><span lang="FA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">بهطور تصادفی به چهار گروه (بیمار-تمرین)، (بیمار-تمرین-ویتامین </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%"><span new="" roman="" style="font-family:" times="">D</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">)، (بیمار- تمرین-دارونما) و (کنترل) تقسیم شدند. پروتکل تمرینی شامل ده هفته فعالیت ورزشی پیلاتس است. گروه مکمل هفتهای سه روز </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%"><span new="" roman="" style="font-family:" times="">IU</span></span></span><span style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:"> 500 ویتامین </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%"><span new="" roman="" style="font-family:" times="">D</span></span></span><span style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:"> را، بهمدت 10 هفته مصرف میکردند. دادهها با استفاده از آزمون </span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:92%"><span new="" roman="" style="font-family:" times="">t</span></span></span><span style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:"> وابسته و تحلیل واریانس یکراهه تجزیهوتحلیل شد.</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus""></span></span></span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:92%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">یافتهها</span></span></span></b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">: </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">نتایج حاصل از تحلیل کوواریانس پژوهش سه گروه تمرینی نشان داد پس از ده هفته بازتوانی ورزشی همراه مصرف ویتامین </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%"><span new="" roman="" style="font-family:" times="">D</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">، </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">شاخصهای خستگی و میزان افسردگی</span></span></span> <span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">کاهش معنادار یافته است (</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">05/0 </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%"><span new="" roman="" style="font-family:" times="">P</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:92%">≤</span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">). و همچنین نتایج حاصل از تحلیل کوواریانس سه گروه تمرینی نشان داد </span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">کیفیت خواب کلی</span></span></span> <span lang="FA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">افراد مبتلا به سرطان استئوسارکوم افزایش</span></span></span> <span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">معنادار یافته است (</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">05/0 </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%"><span new="" roman="" style="font-family:" times="">P</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:92%">≤</span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">).</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus""></span></span></span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:92%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span sans-serif="" style="font-family:Calibri,"><b><span lang="FA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:">نتیجهگیری:</span></span></span></b><span lang="FA" style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:"> ﺑﺮاﺳﺎس ﻧﺘﺎﻳﺞ ﺑﻪدﺳﺖ آﻣﺪه ﭘﻴﺸﻨﻬﺎد ﻣﻲﺷﻮد ﻣﺼﺮف ویتامین </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%"><span new="" roman="" style="font-family:" times="">D</span></span></span><span style="font-size:12.0pt"><span style="line-height:92%"><span b="" lotus="" style="font-family:"> به همراه بازتوانی ورزشی ﻣﻲﺗﻮاﻧﺪ ﺷﻴﻮۀ درﻣﺎﻧﻲ ﻣﺆﺛﺮی ﺑﺮای بر خستگی، کیفیت خواب و میزان افسردگی افراد مبتلا به سرطان استئوسارکوم ﺑﺎﺷﺪ.</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"Times New Roman","serif""></span></span></span></span></span></span></span></span><br>
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<span style="font-size:11pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="line-height:107%"><span sans-serif="" style="font-family:Calibri,"><span dir="LTR" style="font-size:12.0pt"><span style="line-height:107%"><span style="font-family:"Times New Roman","serif""></span></span></span></span></span></span></span></span>
<span style="font-size:11pt"><span style="tab-stops:right 0cm"><span style="line-height:107%"><span sans-serif="" style="font-family:Calibri,"><b><span new="" roman="" style="font-family:" times="">Background:</span></b><span new="" roman="" style="font-family:" times=""> The purpose of this study was to investigate the effect of sports rehabilitation exercises with vitamin D consumption on fatigue, sleep quality and depression level of people with osteosarcoma cancer after bone marrow stem cell transplantation.</span></span></span></span></span><br>
<span style="font-size:11pt"><span style="tab-stops:right 0cm"><span style="line-height:107%"><span sans-serif="" style="font-family:Calibri,"><b><span new="" roman="" style="font-family:" times="">Methods:</span></b><span new="" roman="" style="font-family:" times=""> In this study, 27 women with osteosarcoma cancer with body mass index above 30 kg/m2, age 24.90±4.03 years, height 163.85±3.62 cm and weight 82.17±4.5 kg were randomly divided into four groups. (patient-exercise), (patient-exercise-vitamin D), (patient-exercise-placebo) and (control) were divided. The training protocol includes ten weeks of Pilates exercise. The supplement group took 500 IU of vitamin D three days a week for 10 weeks. Data were analyzed using dependent t-test and one-way analysis of variance.</span></span></span></span></span><br>
<span style="font-size:11pt"><span style="tab-stops:right 0cm"><span style="line-height:107%"><span sans-serif="" style="font-family:Calibri,"><b><span new="" roman="" style="font-family:" times="">Results:</span></b><span new="" roman="" style="font-family:" times=""> The results of the covariance analysis of the research of three exercise groups showed that after ten weeks of sports rehabilitation with vitamin D consumption, the indicators of fatigue and the level of depression decreased significantly (P≤ 0.05). Also, the results of covariance analysis of the three training <span style="letter-spacing:-.2pt">groups showed that the overall sleep quality of people with osteosarcoma cancer increased significantly (P≤ 0.05).</span> Conclusion: Based on the obtained results, it is suggested that the consumption of vitamin D along with exercise rehabilitation can be an effective treatment method for fatigue, sleep quality and depression in people with osteosarcoma cancer.</span><span dir="RTL" lang="AR-SA" style="font-size:14.0pt"><span style="font-family:"B Lotus""></span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="tab-stops:right 0cm"><span style="line-height:107%"><span sans-serif="" style="font-family:Calibri,"><b><span new="" roman="" style="font-family:" times="">Conclusion:</span></b> <span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times="">Based on the obtained results, it is suggested that the consumption of vitamin D along with sports rehabilitation can be an effective treatment method for fatigue, sleep quality and depression in people with osteosarcoma cancer.</span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:normal"><span sans-serif="" style="font-family:Calibri,"><span dir="RTL" lang="FA" style="font-size:12.0pt"><span style="font-family:"B Nazanin""></span></span></span></span></span>
ویتامین D, بازتوانی, استئوسارکوم, افسردگی, سلولهای بنیادی
Vitamin D, Rehabilitation, Osteosarcoma, Depression, Stem cells
142
153
http://ijdld.tums.ac.ir/browse.php?a_code=A-10-707-4&slc_lang=fa&sid=1
Asma
Soleimani
اسما
سلیمانی