Iranian Journal of Diabetes and Lipid Disorders
مجله دیابت و متابولیسم ایران
ijdld
Medical Sciences
http://ijdld.tums.ac.ir
1
admin
2345-4008
2345-4016
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000
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fa
jalali
1403
9
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gregorian
2024
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بررسی تغییرات هپاتوکاین فتوئین A و مقاومت به انسولین متعاقب یک دورۀ تمرین تناوبی طنابزنی در مردان جوان دارای اضافه وزن و چاق
Investigating The Changes of Hepotokine Fetuin-A and Insulin Resistance following a period of Jump Rope Interval Training in Overweight and Obese Young Men
تخصصي
Special
پژوهشي
Research
<span style="font-size:11pt"><span style="line-height:92%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Calibri",sans-serif"><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">مقدمه:</span></span></span></b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus""> مداخلات ورزشی میتواند نقشی مهمی در بهبود وضعیت متابولیکی بهواسطۀ تنظیم هپاتوکینها داشته باشد. هدف از پژوهش حاضر، بررسی اثر هشت هفته تمرین تناوبی طنابزنی بر مقادیر سرمی فتوئین </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%"><span style="font-family:"Times New Roman",serif">A</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus""> و مقاومت به انسولین در مردان جوان دارای اضافه وزن و چاق بود. </span></span></span><b><span dir="LTR" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"Times New Roman",serif"></span></span></span></b></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:92%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Calibri",sans-serif"><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">روش‏ها:</span></span></span></b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus""> در </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">این مطالعۀ نیمهتجربی، 26 مرد جوان دارای اضافه وزن و چاق (نمایۀ تودۀ بدن: </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">66/1</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"Cambria",serif">±</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">24/28</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">) داوطلبانه و بهصورت هدفمند بهعنوان نمونه آماری انتخاب و به شکل تصادفی در دو گروه تجربی (13 نفر) و کنترل (13 نفر) تقسیم شدند. شرکتکنندگان گروه تجربی بهمدت هشت هفته (چهار جلسه در هفته/ هر جلسه 40 دقیقه) به انجام تمرینهای تناوبی طنابزنی پرداختند. در ابتدا و انتهای پژوهش، نمونۀ خون وریدی برای اندازهگیری مقادیر فتوئین </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%"><span style="font-family:"Times New Roman",serif">A</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus""> و مقاومت به انسولین جمعآوری شد. تجزیهوتحلیل دادهها با استفاده از نرمافزار </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%"><span style="font-family:"Times New Roman",serif">SPSS</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus""> نسخۀ 22 و با آزمون </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">آماری تی وابسته و مستقل </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">در سطح معناداری کمتر از 05/0 انجام شد</span></span></span><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">.</span></span></span></b></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:92%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Calibri",sans-serif"><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">یافتهها: </span></span></span></b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">بعد از انجام هشت هفته تمرین تناوبی طنابزنی کاهش معناداری در </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">مقادیر سرمی </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">فتوئین </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%"><span style="font-family:"Times New Roman",serif">A</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">،</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus""> مقاومت به انسولین و درصد چربی بدن</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus""> در گروه تجربی مشاهده شد </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">(05/0 </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%"><span style="font-family:"Times New Roman",serif">P≤</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">). </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">علاوه بر این اختلاف معناداری بین دو گروه تجربی و کنترل در </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">مقادیر سرمی </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">فتوئین </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%"><span style="font-family:"Times New Roman",serif">A</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">،</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus""> مقاومت به انسولین و درصد چربی بدن </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">مشاهده شد </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">(05/0 </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%"><span style="font-family:"Times New Roman",serif">P≤</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">).</span></span></span><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus""></span></span></span></b></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:92%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span style="font-family:"Calibri",sans-serif"><b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">نتیجهگیری:</span></span></span></b><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus""> با توجه به نتایج پژوهش حاضر بهنظر میرسد که انجام تمرین تناوبی طنابزنی منظم بهمدت هشت هفته میتواند با کاهش مقادیر سرمی هپاتوکاین فتوئین </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%"><span style="font-family:"Times New Roman",serif">A</span></span></span> <span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:92%"><span style="font-family:"B Lotus"">در بهبود وضعیت متابولیکی در مردان جوان دارای اضافه وزن و چاق نقش مؤثری داشته باشد.</span></span></span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:92%"><span style="tab-stops:right 0cm"><span style="font-family:"Calibri",sans-serif"><b><span style="line-height:92%"><span style="font-family:"Times New Roman",serif">Background:</span></span></b><span style="line-height:92%"><span style="font-family:"Times New Roman",serif"> <span style="background:white"><span style="color:black">Exercise interventions can play an important role in improving metabolic status by regulating hepotokines. The present study aimed to investigate the effect of eight weeks of Jump Rope Interval Training on serum levels of Fetuin-A and insulin resistance in overweight and obese young men.</span></span><span style="background:white"></span></span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:92%"><span style="tab-stops:right 0cm"><span style="font-family:"Calibri",sans-serif"><b><span style="line-height:92%"><span style="font-family:"Times New Roman Bold",serif">Methods:</span></span></b> <span style="font-family:"Times New Roman",serif">In this semi-experimental study, 26 overweight and obese young men (body mass index: 28.24±1.66) were voluntarily and purposefully selected as a statistical sample and randomly divided into two experimental (n= 13) and control (n= 13) groups. The participants of the experimental group performed Jump Rope Interval Training for 8 weeks (four sessions per week/40 minutes each session). At the beginning and end of the study, venous blood samples were collected to measure Fetuin-A and insulin resistance. Data analysis was done using SPSS software version 24 and with dependent and independent t-tests at a significance level of less than 0.05.</span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:92%"><span style="tab-stops:right 0cm"><span style="font-family:"Calibri",sans-serif"><b><span style="line-height:92%"><span style="font-family:"Times New Roman",serif">Results:</span></span></b><span style="line-height:92%"><span style="font-family:"Times New Roman",serif"> After 8 weeks of Jump Rope Interval Training, a significant decrease was observed in serum levels of Fetuin-A, insulin resistance and, body fat percentage (P≤ 0.05). Also, a significant difference was observed between the experimental and control groups in serum levels of Fetuin-A, insulin resistance and, body fat percentage (P≤ 0.05).</span></span><span dir="RTL" lang="FA" style="font-size:14.0pt"><span style="line-height:92%"><span style="font-family:"Times New Roman",serif"></span></span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:92%"><span style="font-family:"Calibri",sans-serif"><b><span style="line-height:92%"><span style="font-family:"Times New Roman",serif">Conclusion:</span></span></b><span style="line-height:92%"><span style="font-family:"Times New Roman",serif"> According to the results of the present study, it seems that regular jump rope interval training for eight weeks can effectively improve the metabolic complications in overweight and obese young men by reducing the serum levels of hepotokine Fetuin-A.</span></span></span></span></span><br>
تمرین تناوبی, هپاتوکاین, مقاومت به انسولین, اضافه وزن و چاق
Interval Training, Hepotokines, Insulin Resistance, Overweight and Obese
330
338
http://ijdld.tums.ac.ir/browse.php?a_code=A-10-2085-2&slc_lang=fa&sid=1
Bizhan
Hooshmand Moghadam
بیژن
هوشمند مقدم