Volume 15, Issue 3 (2-2016)                   ijdld 2016, 15(3): 177-182 | Back to browse issues page

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Alah gahi F, Shiravi A, Hojati V. EFFECT OF ALCOHOLIC EXTRACT OF GRAPE (VITIS VINIFERA) ON WOUND HEALING DIABETIC MALE WISTAR RATS. ijdld 2016; 15 (3) :177-182
URL: http://ijdld.tums.ac.ir/article-1-5337-en.html
1- Department of Biology, Damghan Branch, Islamic Azad University, Damghan, Iran
Abstract:   (6700 Views)

Background: Finding effective drugs have been considered for healing diabetic wounds by researchers. The purpose of this study was to evaluate the effects on wound healing ointment Alcoholic extract of grape seed skin is normal and diabetic rats.

Methods:  In this study 48 male Wistar rats into four groups (negative control, positive control, the first experimental, the second experimental) were divided. Groups tested in the injured area of 3 cm2   were created on the left spine. The wound healing was evaluated macroscopically. The results are reported as Mean ± SD. Statistical inference border (P ≥0.05) and (P ≥0.01) and (P ≥0.001).

Results: Compared with normal wound healing in diabetic groups were later and Wound healing in experimental groups treated with Vitis Vinifera more quickly than the control group, respectively.

Conclusions: In this study the skin ointment Vitis Vinifera accelerates the wound healing is normal and diabetic samples.

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Type of Study: Research | Subject: Special
Received: 2015/04/18 | Accepted: 2015/12/19 | Published: 2016/04/20

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