1- Department of Sports Physiology, Faculty of Educational Sciences and Psychology, Mohaghegh Ardabili University, Ardabil, Iran
2- Department of Sports Physiology, Faculty of Educational Sciences and Psychology, Mohaghegh Ardabili University, Ardabil, Iran , f.seify@yahoo.com
2- Department of Sports Physiology, Faculty of Educational Sciences and Psychology, Mohaghegh Ardabili University, Ardabil, Iran , f.seify@yahoo.com
Abstract: (108 Views)
Introduction: The present study aimed to investigate the changes in TRx-sh/TRx-s2 levels, GSH values, and total antioxidant capacity following 8 weeks of intense interval training with and without citrate supplementation in diabetic rats.
Methodology: In this semi-experimental and fundamental study, 50 male Wistar rats were randomly divided into 5 groups: healthy control, control control, selective - exercise, consumption-sodium citrate supplementation, and drink-sodium citrate supplementation.72 hours after the last training session, blood was taken from the abdominal vena cava for research studies using the ELISA method. To compare the study groups, a one-way analysis of variance and LSD post hoc test were used in SPSS software (p≥0.05).
Findings: The results showed that the levels of TRx-sh/TRx-s2, GSH, and TAC were significantly different among the five research groups (p<0.001). Also, the results showed the levels of TRx-sh/TRx-s2, TAC, and GSH in the control-diabetic group (P<0.001), diabetic-exercise (P<0.001), and diabetic-supplement group (P=0.001). and diabetic-supplement-exercise (P<0.001) had a significant decrease compared to the healthy control group. The levels of TRx-sh/TRx-s2, GSH, and TAC in the diabetic-supplement and diabetic-supplement-exercise groups were significantly increased compared to the diabetic control group (P<0.05). According to the difference in means, the increase of TRx-sh/TRx-s2, TAC, and GSH was higher in the diabetic-supplemented group.
Conclusion: According to the results of the research, it can be assumed that sodium citrate supplementation is effective in improving diabetes and this effect is probably exerted by increasing TRx-sh/TRx-s2, TAC, and GSH.
Methodology: In this semi-experimental and fundamental study, 50 male Wistar rats were randomly divided into 5 groups: healthy control, control control, selective - exercise, consumption-sodium citrate supplementation, and drink-sodium citrate supplementation.72 hours after the last training session, blood was taken from the abdominal vena cava for research studies using the ELISA method. To compare the study groups, a one-way analysis of variance and LSD post hoc test were used in SPSS software (p≥0.05).
Findings: The results showed that the levels of TRx-sh/TRx-s2, GSH, and TAC were significantly different among the five research groups (p<0.001). Also, the results showed the levels of TRx-sh/TRx-s2, TAC, and GSH in the control-diabetic group (P<0.001), diabetic-exercise (P<0.001), and diabetic-supplement group (P=0.001). and diabetic-supplement-exercise (P<0.001) had a significant decrease compared to the healthy control group. The levels of TRx-sh/TRx-s2, GSH, and TAC in the diabetic-supplement and diabetic-supplement-exercise groups were significantly increased compared to the diabetic control group (P<0.05). According to the difference in means, the increase of TRx-sh/TRx-s2, TAC, and GSH was higher in the diabetic-supplemented group.
Conclusion: According to the results of the research, it can be assumed that sodium citrate supplementation is effective in improving diabetes and this effect is probably exerted by increasing TRx-sh/TRx-s2, TAC, and GSH.
Article number: 11
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